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Villarreal vs Manchester City Prediction, Preview, Team News and Lineups 21.10.2025

. Estadio de la Ceramica

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Who Will Win This Match?

All Competitions
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  • L
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All Competitions
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LAST GAME: Villarreal 2 - 2 Real Betis
  • LaLiga Santander
  • Oct 18, 2025 at 4:30 pm
  • Estadio de la Cerámica
LAST GAME: Manchester City 2 - 0 Everton
  • Premier League
  • Oct 18, 2025 at 2:00 pm
  • Etihad Stadium
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Event Details

  • Date and Time: Tuesday, October 21, 2025, 3:00 PM EDT
  • Venue: Estadio de la Cerámica, Villarreal, Spain
  • Competition: Champions League
Odds via 20Bet
Villarreal vs Manchester CityTuesday, October 21, 2025, 3:00 PM EDT
Villarreal odds+359
Manchester City odds-137
Draw+309
Over/UnderTotal 2.5: -162/+136
Betting BonusUp to 100 $/€

Villarreal vs Manchester City Preview and Team News 

Villarreal Team News

Villarreal find themselves in a precarious position in the competition with just a single point from their opening two fixtures, needing a positive result to climb the table.

The Yellow Submarine drew 2-2 with Juventus in their previous Champions League clash after losing their opening match to Tottenham.

Villarreal currently sit third in La Liga with an impressive record. In their latest outing against Betis, they squandered a two-goal lead and conceded a 94th-minute equalizer to settle for a 2-2 draw.

This result left manager Marcelino García Toral questioning his side’s ability to close out games in key moments. In their previous La Liga encounter, the team suffered a 1-3 defeat to Real Madrid.

Despite the loss, Villarreal created several dangerous opportunities, particularly through the pace of their attacking transitions. Still, the meeting highlighted their defensive vulnerabilities against elite attacking talent, which can be a problem facing Erling Haaland’s goal threat.

Earlier, the Yellow Submarine had gone unbeaten in several matches at the Estadio de la Cerámica, where their last competitive defeat came in March 2025 when Real Madrid beat them 1-2.

Villarreal will be without Pau Cabanes, Willy Kambwala, and Juan Foyth, all sidelined with injuries. 

Villarreal predicted lineup vs Manchester City (4-3-3): Tenas; Mouriño, Marín, Veiga, Cardona; Gueye, Parejo, Comesana; Pépé, Mikautadze, Buchanan.

Manchester City Team News

Manchester City have shown big improvement compared to their early-season struggles. The Citizens are currently on an eight-game unbeaten streak across all competitions.

In their most recent outing, Erling Haaland’s impressive second-half brace helped Manchester City grab a 2-0 Premier League victory over Everton at the Etihad, moving them up to second place in the league standings.

The Norwegian forward continues his incredible form, having scored in 11 consecutive appearances for club and country. This takes his overall tally to 23 goals this season, with 14 for City, including 11 in the league. 

His ability to find space in tight areas and convert half-chances into goals makes him arguably the most dangerous striker in world soccer at the moment.

In the Champions League, Man City secured a 2-0 win against Napoli in their opening match but drew 2-2 with Monaco in their second.

The biggest concern is the fitness of key players. Rodri missed the last fixture with a hamstring injury sustained 22 minutes into City’s win over Brentford, and Rayan Aït-Nouri has missed eight encounters with an ankle injury, though Guardiola mentioned the left-back is close to a return.

Additionally, Abdukodir Khusanov remains a doubt due to fitness issues. 

Manchester City predicted lineup vs Villarreal (4-1-4-1): Donnarumma; Nunes, Stones, Gvardiol, O’Reilly; Gonzalez; Bobb, Silva, Foden, Doku; Haaland.

Villarreal vs Manchester City Prediction 

  • Pick: draw or Manchester City
  • Odds: -455 (20Bet)
  • Score prediction: Villarreal 2-2 Manchester City

Manchester City’s superior technical quality, combined with Erling Haaland’s extraordinary goal-scoring form, should prove decisive in this match.

However, Villarreal’s impressive home record and desperate need for points could motivate them to play with high intensity and organization. Their ability to defend deep and counterattack through dangerous wide players like Tajon Buchanan and Nicolas Pépé could create uncomfortable moments for the visitors’ vulnerable defense. 

The absence of Rodri removes a crucial element of City’s defensive structure, potentially leaving space for Villarreal to exploit on the break.

However, the English side’s relentless pressure and Haaland’s clinical finishing should eventually provide a positive result for the guests.

Villarreal vs Manchester City Prediction, Betting Tip

  • Pick: Both teams to score
  • Odds: -157 (20Bet

Villarreal have demonstrated their ability to score against top opponents like Juventus and Real Madrid. They have great counterattacking cohesion and can exploit their opponents’ weakness with a high defensive line. 

Man City have looked defensively vulnerable at times in recent matches against Everton, Monaco, and Brentford, allowing several big chances despite dominating possession.

We can expect both teams to find the net, with Villarreal likely capitalizing on at least one counterattacking opportunity and the Citizens‘ high quality in positional attacks producing several goals.

Villarreal vs Manchester City Where to Watch (USA, Canada) 

  • NBC (USA)
  • DAZN (Canada)

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