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Top UEFA Champions League Predictions and Picks – Knockout Phase, Round of 16

Bayer 04 Leverkusen Bayer 04 Leverkusen
UEFA Champions League. Play-off. Round of 16 Mar 11, 2025 at 8:00 pm BayArena
Bayern Munich Bayern Munich
Bayer 04 Leverkusen winsDrawBayern Munich wins
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LAST GAME: Bayer Leverkusen 0 - 2 Werder Bremen
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  • Mar 08, 2025 at 2:30 pm
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LAST GAME: Bayern Munich 2 - 3 Bochum
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The round of 16 stage of the UEFA Champions League is here – with the first legs of the matches done and dusted, the real knockout phase has begun! 

So without any further ado, let us dig right into our picks and predictions for the best matches of this round!

Top UEFA Champions League prediction №1. Bayer Leverkusen vs Bayern Munich (Tuesday, March 11)

Bayer Leverkusen will host Bayern Munich in one of the biggest matches of this round of the Champions League. The two German clubs have been at loggerheads with each other from last season, ever since Leverkusen won the league and established their dominance over proceedings. 

​Here is a summary of the recent head-to-head matches between Bayer Leverkusen and Bayern Munich:​

DateCompetitionResult
5 March 2025Champions LeagueBayern Munich 3 – 0 Bayer Leverkusen
15 February 2025BundesligaBayer Leverkusen 0 – 0 Bayern Munich
3 December 2024DFB-PokalBayern Munich 0 – 1 Bayer Leverkusen
28 September 2024BundesligaBayern Munich 1 – 1 Bayer Leverkusen
10 February 2024BundesligaBayer Leverkusen 3 – 0 Bayern Munich
15 September 2023BundesligaBayern Munich 2 – 2 Bayer Leverkusen

This time around, however, the hosts are at a disadvantage as they were soundly beaten 0-3 by Bayern in the first leg. Harry Kane will be the player to watch out for in this round, and Bayern will rely heavily upon his services in the final third.

  • Pick: Bayern Munich to win or draw (-222)

Top UEFA Champions League prediction №2. Liverpool vs Paris Saint-Germain (Tuesday, March 11)

Liverpool, who practically got away with daylight robbery by beating Paris Saint-Germain 1-0 in the first leg of their encounter even though they took just two shots all game, will have a much harder task this time around. 

PSG seem rejuvenated this season under Luis Enrique, and they will put up a fight in this match, with Ousmane Dembele leading from the front. 

PSG will prove to be a tough challenge for Liverpool in this game, and the latter will have to overcome this if they intend to win the tournament and establish their superiority all over Liverpool. This will be a close encounter for sure.

  • Pick: Liverpool to win or draw (-238)

Top UEFA Champions League prediction №3. Inter Milan vs Feyenoord (Tuesday, March 11)

Inter Milan vs Feyenoord will be another interesting game to watch in this round of the Champions League. Inter won the first leg away from home 2-0, and will surely start with an advantage in this game. Feyenoord are, however, known for making strong comebacks, and this will be the flavour of this encounter as well. 

Nonetheless, Inter are renowned for their tactical superiority and defensive organisation, which is bound to give them an upper hand. Plus, the fact that they are playing at home will work to their favour, at least sentimentally and emotionally.

  • Pick: Inter Milan to win (-278)

Top UEFA Champions League prediction №4. Barcelona vs Benfica (Tuesday, March 11)

Barcelona take on Benfica for another fine encounter in the UEFA Champions League in this round. What makes this match exciting is the fact that Barca won the first leg by a narrow 1-0 scoreline, and will be under huge pressure to do well this time around.

However, manager Hansi Flick is not messing around this season, and he will come out with all guns blazing to pick up a win here, especially in front of their home fans. Barca are known for their flamboyant passing game, and incisive nature in the final third. Against Benfica, they will have to guard against letting complacency creep in and also protect their defensive frailties by not losing the ball too often.

  • Pick: Barcelona to win (-270)

Top UEFA Champions League prediction №5. Atletico Madrid vs Real Madrid (Wednesday, March 12)

Perhaps the most interesting encounter of this round of the Champions League will be between Atletico Madrid and Real Madrid in a Madrid derby. This is going to be a close-run encounter as Madrid won the first leg by the narrowest of margins of 2-1. Atletico, playing at home this time around, will have an advantage as they usually keep the ball more often at the Wanda Metropolitano. 

Antoine Griezmann, who has scored seven goals so far in the UEFA Champions League this season, will be the player to watch out for in the home team while Kylian Mbappé, in Real Madrid’s colours, quite naturally, will be the one who the crowds will come to watch.

  • Pick: Atletico Madrid to win or draw (-233)

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