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Tottenham Hotspur vs Villarreal Prediction, Preview, Team News and Lineups 16.09.2025

Tottenham Hotspur Tottenham Hotspur
UEFA Champions League. League phase. Round 1 Sep 16, 2025 at 7:00 pm Tottenham Hotspur Stadium
Villarreal Villarreal

Tottenham Hotspur winsDrawVillarreal wins
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Who Will Win This Match?

Tottenham HotspurVillarreal
All Competitions
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  • L
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  • D
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All Competitions
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LAST GAME: West Ham United 0 - 3 Tottenham Hotspur
  • Premier League
  • Sep 13, 2025 at 4:30 pm
  • London Stadium
LAST GAME: Atletico Madrid 2 - 0 Villarreal
  • LaLiga Santander
  • Sep 13, 2025 at 7:00 pm
  • Riyadh Air Metropolitano
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Event Details

  • Date and Time: Tuesday, September 16, 2025, 3:00 PM EDT
  • Venue: Tottenham Hotspur Stadium, London, England
  • Competition: UEFA Champions League
Odds via 20Bet
Tottenham Hotspur vs VillarrealTuesday, September 16, 2025, 3:00 PM EDT
Tottenham Hotspur Odds-120
Villarreal Odds+304
Draw+282
Over 2.5-130
Betting BonusUp to 100 $/€

Tottenham Hotspur vs Villarreal Preview and Team News

Tottenham Hotspur Team News

Thomas Frank has enjoyed an excellent start to life at Tottenham Hotspur, with the North London club sitting third in the Premier League standings after wins in three of their opening four fixtures. 

Spurs exceled at both ends of the field in a recent 3-0 victory over West Ham, creating 14 chances from their 64% possession. Frank must have been delighted with how secure his team were when they had the ball, accumulating a pass accuracy of 87%.

 Xavi Simons looked assured on his Tottenham debut, while Mohammed Kudus was a constant threat on the right-hand side of the forward three in the 4-3-3 formation. 

Richarlison could replace Tel in the starting eleven, as the latter was omitted from their Champions League squad. 

Tottenham Hotspur predicted lineup vs Villarreal (4-3-3): Vicario; Porro, Romero, van de Ven, Spence; Bergvall, Palhinha, Sarr; Kudus, Richarlison, Simons.

Villarreal Team News

Villarreal could present an interesting challenge for Tottenham this week, as Marcelino Garcia Toral’s men have won half of their four La Liga matches this season. 

However, a response will be expected from the coach following a disappointing 2-0 defeat against Atletico Madrid on Saturday. The Yellow Submarine attempted to play on the counter in that clash, but they mustered just a single shot on target. It could be argued that they were too passive in the Spanish capital, as they had just 39% of the ball. 

Despite that, Toral is likely to stick with the 4-4-2 system on Tuesday. Thomas Partey could feature against Premier League opposition for the first time since joining the Spanish club. Meanwhile, Tajon Buchanan should remain a constant threat on the break from the right side of the midfield four. 

Villarreal predicted lineup vs Tottenham Hotspur (4-4-2): Junior; Mourino, Foyth, Veiga, Cardona; Buchanan, Partey, Parejo, Moleiro; Mikautadze, Pepe.

Tottenham Hotspur vs Villarreal Prediction 

  • Pick: Draw
  • Odds: +282 (20Bet)
  • Correct score prediction: Tottenham Hotspur 1-1 Villarreal

Tottenham have struggled against Spanish opposition throughout their modern European history, winning just one of their last 13 encounters. 

Villarreal could find plenty of joy on the counterattack this week, with their pacey players in wide areas breaking at speed after winning back possession. Spurs have already shown vulnerability in transitions this season, and that weakness could see them drop points in their Champions League opener on Tuesday. As a result, the draw looks like a realistic option.

Tottenham Hotspur vs Villarreal Prediction, Betting Tip

  • Pick: Under 3.5 Cards
  • Odds: -104 (20Bet)

Tottenham and Villarreal have both been well-disciplined in the opening weeks of their respective domestic campaigns. The fact that both teams are well-drilled means that they’re rarely caught out of possession. 

That is indicated by their number of yellow cards, with the hosts averaging 1.75 per 90 minutes and the visitors posting the same figure. Based on these trends, it could be worth taking a chance on under 3.5 cards being issued in London on Tuesday. 

Tottenham Hotspur vs Villarreal Where to Watch (USA, Canada) 

  • CBS (USA)
  • DAZN (Canada)

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