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Real Madrid vs Manchester City Prediction, Preview, Team News and Lineups 10.12.2025

09/12/25 Mark Sochon
Real Madrid vs Manchester City Prediction, Preview, Team News and Lineups
Real Madrid Real Madrid
UEFA Champions League. League phase. Round 6 Dec 10, 2025 at 8:00 pm Estadio Santiago Bernabéu
Manchester City Manchester City

Real Madrid winsDrawManchester City wins
2.663.782.425
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Who Will Win This Match?

Real MadridManchester City
All Competitions
  • L
  • W
  • D
  • W
  • D
  • D
All Competitions
  • W
  • W
  • W
  • L
  • L
  • W
LAST GAME: Real Madrid 0 - 2 Celta Vigo
  • LaLiga Santander
  • Dec 07, 2025 at 8:00 pm
  • Estadio Santiago Bernabéu
LAST GAME: Manchester City 3 - 0 Sunderland
  • Premier League
  • Dec 06, 2025 at 3:00 pm
  • Etihad Stadium
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Event Details

  • Date and Time: Wednesday, December 10, 2025, 3:00 PM EST
  • Venue: Santiago Bernabéu, Madrid, Spain
  • Competition: UEFA Champions League
Odds via 20Bet
Real Madrid vs Manchester CityWednesday, December 10, 2025, 3:00 PM EST
Real Madrid odds+150
Manchester City odds+160
Draw+285
Over 2-500
Betting BonusUp to 100 $/€

Real Madrid vs Manchester City Preview and Team News

Real Madrid Team News

This is an enormous match for Xabi Alonso, who is now under genuine pressure after a poor run of form. Real Madrid have only won two of their last seven games across all competitions. That sequence culminated in a desperate 2-0 home defeat against Celta Vigo on Sunday.

Media reports suggest the ex-Bayer Leverkusen boss may have already lost the dressing room. His public fall-out with Vinícius Júnior has been well documented, but it now seems many other players are unhappy and underperforming.

Against Celta at the weekend, their high line was exploited on many occasions, with a fresh injury sustained by Éder Militão early in that meeting adding to their defensive problems. At the other end, they’ve been far too dependent on moments of brilliance from Kylian Mbappé, with no sign of a clear playing identity developing.

Trent Alexander-Arnold, Dani Carvajal, and Ferland Mendy are also currently sidelined, while they have additional fitness doubts over David Alaba, Eduardo Camavinga, and Dean Huijsen.

Real Madrid predicted lineup vs Manchester City (4-1-3-2): Courtois; Carreras, Asencio, Rüdiger, Valverde; Tchouaméni; Güler, Bellingham, Ceballos; Vinícius, Mbappé.

Manchester City Team News

From a Manchester City perspective, this fixture is all about trying to take points off a direct rival for a top-eight finish in the initial phase of the Champions League. They’re just outside those places currently, following a 2-0 defeat at home against Bayer Leverkusen on matchday five.

Pep Guardiola paid the price for resting star striker Erling Haaland in that game. However, his team have bounced back well with three straight wins in the Premier League and 11 goals scored. 

A 4-3-2-1 structure has worked nicely in recent outings, with Rayan Cherki and Jérémy Doku both excelling in advanced roles behind the Norwegian striker in the 3-0 weekend win over Sunderland.

Cherki is pushing hard for a first Champions League start for the Sky Blues on Wednesday, although a slightly more conservative system is expected. The visitors will have to cope without the injured trio of Rodri, John Stones, and Mateo Kovačić.

Manchester City predicted lineup vs Real Madrid (4-1-4-1): Donnarumma; Nunes, Dias, Gvardiol, O’Reilly; González; Cherki, Reijnders, Foden, Doku; Haaland.

Real Madrid vs Manchester City Prediction 

  • Pick: Manchester City to win
  • Odds: +160 (20Bet)
  • Correct score prediction: Real Madrid 1-2 Manchester City

Real Madrid are in a really bad state right now, with little sign that the coach and players are on the same page. Reports indicate much of this squad would already welcome a change in the dugout, and that suggests we won’t get a passionate response to a poor weekend performance from the home side.

There is more clarity to what Man City are trying to do. While they also have a reliance on one exceptional striker, the movement and creativity of the likes of Cherki, Doku, and Phil Foden ensure they do carry other threats, and there’s a much greater sense of team harmony. That suggests the value lies with the visitors here.

Real Madrid vs Manchester City Prediction, Betting Tip

  • Pick: Erling Haaland to score anytime
  • Odds: -110 (20Bet)

There are big selection problems at the back for Real Madrid, which doesn’t bode well for their chances of handling Haaland. Militão is expected to be out for at least three months, and he’s been their most convincing center-back. Raúl Asencio may be drafted into the lineup here as a result, but he lacks the physicality to deal with the City frontman.

Haaland has scored 20 times in 20 appearances for the English club this season. The 25-year-old looks to offer value to fire against a weakened home defense.

Real Madrid vs Manchester City Where to Watch (USA, Canada)

  • DAZN (USA)
  • DAZN (Canada)

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