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Liverpool vs Real Madrid Prediction, Preview, Team News and Lineups 04.11.2025

Liverpool Liverpool
UEFA Champions League. League phase. Round 4 Nov 04, 2025 at 8:00 pm Anfield
Real Madrid Real Madrid

Liverpool winsDrawReal Madrid wins
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Who Will Win This Match?

LiverpoolReal Madrid
All Competitions
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  • L
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All Competitions
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LAST GAME: Liverpool 2 - 0 Aston Villa
  • Premier League
  • Nov 01, 2025 at 8:00 pm
  • Anfield
LAST GAME: Real Madrid 4 - 0 Valencia
  • LaLiga Santander
  • Nov 01, 2025 at 8:00 pm
  • Estadio Santiago Bernabéu
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Event Details

  • Date and Time: Tuesday, November 4, 2025, 3:00 PM EST
  • Venue: Anfield, Liverpool, England
  • Competition: Champions League
Odds via 20Bet
Liverpool vs Real MadridTuesday, November 4, 2025, 3:00 PM EST
Liverpool odds+154
Real Madrid odds+154
Draw+290
Over/UnderTotal 2.5: -223/+185
Betting BonusUp to 100 $/€

Liverpool vs Real Madrid Preview and Team News 

Liverpool Team News

Liverpool halted a disappointing run with six losses out of seven matches across all competitions by securing a victory over Aston Villa. This win ended a four-game losing streak in the Premier League, which had damaged their title defense campaign.

Their performance against Aston Villa demonstrated renewed defensive solidity, which resulted in their first clean sheet in 11 encounters. 

Arne Slot chose not to experiment with the asymmetrical 4-2-3-1 formation, which he had previously used, with Mohamed Salah and Hugo Ekitike leading the press. Instead, he opted for a more straightforward 4-4-2 formation. In this setup, Dominik Szoboszlai led the press alongside Ekitike. The Hungarian midfielder applied clever and powerful pressure on Aston Villa’s center-backs, which proved very effective and resulted in the first goal of the fixture.

Additionally, Liverpool played more cautiously in their rest defense, keeping five to six players ready to switch immediately from attacking to defending. This approach helped limit Villa’s counterattacking threat.

The Reds’ defensive issues this season have also stemmed from personnel changes, particularly the addition of Florian Wirtz, who provides less defensive cover than Szoboszlai.

Additionally, Slot himself acknowledged that Liverpool are conceding too many goals, identifying crosses and counterattacks as key issues, with opponents increasingly targeting quick transitions and aerial deliveries to exploit space behind their high defensive line.

As for injuries, Alisson Becker’s return may come too soon, though he could be fully fit to face Manchester City this weekend. Jeremie Frimpong is out with a second hamstring issue of the season and will miss all of November.

Alexander Isak remains doubtful with a groin problem picked up against Frankfurt, while Giovanni Leoni faces a long-term absence following ACL surgery. Stefan Bajcetic and Jayden Danns are also unavailable through injury.

Liverpool predicted lineup vs Real Madrid (4-2-3-1): Mamardashvili; Bradley, Konate, Van Dijk, Robertson; Gravenberch, Mac Allister; Salah, Szoboszlai, Gakpo; Ekitike.

Real Madrid Team News

Real Madrid have been one of the best teams in Europe so far this season, winning 13 of their 14 competitive matches.

Kylian Mbappe scored twice, and Jude Bellingham found the net for the third consecutive game as Los Blancos secured a 4-0 victory over Valencia. Before that, goals from Mbappe and Bellingham earned them a crucial 2-1 win over Barcelona.

In El Clásico, Xabi Alonso implemented a highly flexible defensive strategy. His side used high man-marking pressing in a 4-2-4 formation. When that pressing was broken, Madrid transitioned to a 4-1-4-1 mid-block and occasionally dropped into a 5-3-2 formation when defending deep.

This approach allowed them to exert control over Barcelona, particularly in the latter stages, when they played in a low defensive block, effectively covering their holding zone near the penalty box.

At the same time, Real Madrid showed great counterattacking play, with Jude Bellingham’s through ball for Kylian Mbappe’s opener demonstrating the creative connections developing within Alonso’s system. Mbappe and Bellingham’s partnership continues to flourish. 

Real Madrid will be without central defender Antonio Rudiger for another couple of months due to a muscular problem. Dani Carvajal suffered a knee injury that rules him out of the team’s trip to Anfield and potentially for the rest of 2025.

David Alaba has missed Real Madrid’s latest outings due to a calf issue and remains a doubt, though he’s aiming to return for this fixture.

Real Madrid predicted lineup vs Liverpool (4-2-3-1): Courtois; Alexander-Arnold, Militao, Huijsen, Carreras; Valverde, Tchouameni; Guler, Bellingham, Vinicius Jr; Mbappe.

Liverpool vs Real Madrid Prediction 

  • Pick: Liverpool to win or draw
  • Odds: -193 (20Bet)
  • Score prediction: Liverpool 1-1 Real Madrid

Real Madrid’s defensive organization can limit Liverpool’s attacking opportunities, while their quality in transition should create good chances against the Reds’ vulnerable defense. 

Mbappe’s current form makes him almost unstoppable, and Bellingham’s ability to arrive late into dangerous positions provides another dimension to Madrid’s attacking threat. Additionally, Vinícius Júnior can create great problems for Conor Bradley and Ibrahima Konate on the left flank.

However, Liverpool demonstrated excellent defensive play in their last match against Aston Villa. If they can replicate that performance, they’ll have a strong chance of disrupting Real Madrid’s build-up play. In such a scenario, Slot’s side can also be very effective during attacking transitions.

Furthermore, the Reds will be playing on home ground, where they can implement their trademark aggressiveness and intensity. Thus, I expect Liverpool to avoid defeat this time.

Liverpool vs Real Madrid Prediction, Betting Tip

  • Pick: Total Over 1.5
  • Odds: -715 (20Bet

The most likely scenario is that both teams will score, resulting in a match total that comfortably exceeds 1.5 goals. Liverpool are expected to create opportunities with their skill in wide areas and through high pressing, while Real Madrid’s counterattacking ability with clinical finishing makes them just as likely to find the net.

Liverpool vs Real Madrid Where to Watch (USA, Canada) 

  • NBC (USA)
  • Fubo (Canada)

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