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LAST GAME: Chelsea 2 - 1 Liverpool
| LAST GAME: Manchester United 2 - 0 Sunderland
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Event Details
- Date and Time: Sunday, October 19, 2025, 11:30 AM EDT
- Venue: Anfield, Liverpool, England
- Competition: Premier League
| Odds via 20Bet | |
| Liverpool vs Manchester United | Sunday, October 19, 2025, 11:30 AM EDT |
| Liverpool Odds | -168 |
| Manchester United Odds | +392 |
| Draw | +348 |
| Over 2.5 | -233 |
| Betting Bonus | Up to 100 $/€ |
Liverpool vs Manchester United Preview and Team News
Liverpool Team News
For the first time during his reign, questions are being asked of Arne Slot. The reigning Premier League champions have suffered defeats in each of their last four matches across all competitions, marking the first time they’ve lost successive league games under the Dutchman.
Following a summer of big spending, it’s fair to say that the signings of Wirtz, Isak, Frimpong, and Kerkez have yet to have a positive impact on team performance. Alexander-Arnold’s departure has also diminished Salah’s influence, as the Egyptian is no longer getting the quick service he craves to attack opposing central defenders.
However, Slot is unlikely to stray from his preferred 4-2-3-1 system, and Ekitike could be recalled to offer a pacey option in the offensive areas. Alisson and Konate both remain out.
Liverpool predicted lineup vs Manchester United (4-2-3-1): Mamardashvili; Bradley, Gomes, van Dijk, Robertson; Gravenberch, Jones; Salah, Wirtz, Gakpo; Ekitike.
Manchester United Team News
Ruben Amorim’s long-term future at Manchester United also remains uncertain. In truth, the international break probably came at a good time for the Portuguese, as the club would have found it challenging to fire him after an impressive display against Sunderland.
Man United have now won two of their last three league encounters, but they’ve conceded six and scored just once in their last two outings on the road. Amorim is expected to stick with his 3-4-2-1 system, and Mount could keep his spot after showing his importance in the pressing side of the game in the win over Sunderland.
Sesko is likely to lead the line after scoring two in as many fixtures. Dorgu might be recalled in favor of Amad, as Amorim takes a slightly more defensive approach to the system at Anfield.
Manchester United predicted lineup vs Liverpool (3-4-2-1): Lammens; Yoro, de Ligt, Shaw; Dalot, Ugarte, Fernandes, Dorgu; Mbeumo, Mount; Sesko.
Liverpool vs Manchester United Prediction
- Pick: Draw
- Odds: +348 (20Bet)
- Correct score prediction: Liverpool 1-1 Manchester United
Manchester United have failed to win on their last ten trips to Anfield since January 2016. It’s hard to see that trend changing on Sunday, but this matchup could play perfectly into Amorim’s style, given Liverpool’s inability to defend counterattacks this season.
The Red Devils produced one of their best performances under Amorim in this fixture last term, and they were unfortunate to end the 90 minutes at 2-2. Man United’s main attacking issues have stemmed from trying to break down opponents, but they tend to thrive on the counterattack.
Still, a draw may be the best they can hope for, as it’s difficult to see their shaky defensive record holding up against one of the most talented forward lines in the Premier League.
Liverpool vs Manchester United Prediction, Betting Tip
- Pick: Both teams to score
- Odds: -196 (20Bet)
Manchester United’s pace on the counterattack with high-quality players such as Mbeumo, Sesko, and Cunha could be vitally important on Sunday.
Liverpool have already conceded an xGA of 1.17 goals per game at Anfield in 2025-26, and Man Utd could add to that worrying trend.
However, the Reds also look capable of scoring, having netted 2.33 goals per match in front of their home fans. Therefore, both teams to score could be a standout Liverpool vs. Manchester United prediction this weekend.
Liverpool vs Manchester United Where to Watch (USA, Canada)
- NBC (USA)
- FuboTV (Canada)
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