Log In Sign Up

Arsenal vs Atlético Madrid Prediction, Preview, Team News and Lineups 21.10.2025

. Emirates Stadium

winsDraw wins
Bet Now

Who Will Win This Match?

All Competitions
  • W
  • W
  • W
  • W
  • W
  • D
All Competitions
  • W
  • D
  • D
  • W
  • W
  • W
LAST GAME: Fulham 0 - 1 Arsenal
  • Premier League
  • Oct 18, 2025 at 4:30 pm
  • Craven Cottage
LAST GAME: Atletico Madrid 1 - 0 Osasuna
  • LaLiga Santander
  • Oct 18, 2025 at 7:01 pm
  • Riyadh Air Metropolitano
Bet Now

Event Details

  • Date and Time: Tuesday, October 21, 2025, 3:00 PM EDT
  • Venue: Emirates Stadium, London, England
  • Competition: UEFA Champions League
Odds via 20Bet
Arsenal vs Atlético MadridTuesday, October 21, 2025, 3:00 PM EDT
Arsenal Odds-159
Atlético Madrid Odds+430
Draw+330
Over 2.5-112
Betting BonusUp to 100 $/€

Arsenal vs Atlético Madrid Preview and Team News

Arsenal Team News

It’s been a reliable start to the 2025-26 Champions League for Mikel Arteta’s Arsenal. The Gunners have won each of their opening two matches in the European competition. 

Their overall form is also solid, as evidenced by a recent 1-0 win at Fulham to retain their spot at the Premier League summit. Arteta has kept faith with the 4-3-3 formation in recent weeks, with Eze and Rice playing either side of defensive midfielder Zubimendi. 

Trossard was excellent on the left wing against Fulham, netting the eventual winner in the second period. Merino could be recalled to the starting eleven on Tuesday, as Arteta may look to rotate his starting squad. 

Arsenal predicted lineup vs Atlético Madrid (4-3-3): Raya; White, Saliba, Gabriel, Calafiori; Merino, Zubimendi, Rice; Saka, Gyökeres, Trossard.

Atlético Madrid Team News

Diego Simeone’s Atlético Madrid currently sit fourth in the La Liga standings after winning four of their first nine games in Spain. 

The team made a poor start to the Champions League with a defeat on matchday one, but they quickly got back on track with a fine win against Eintracht Frankfurt

Simeone has deployed a defensively solid 5-3-2 formation throughout the season, with Le Normand, Giménez, and Hancko playing in the central defensive position. 

The energetic trio of Barrios, Koke, and Baena are key in the middle of the field. Meanwhile, the attacking duo of Griezmann and Alvarez ensure that Atlético have world-class attacking talent at the top of the pitch. 

Atlético Madrid predicted lineup vs Arsenal (5-3-2): Oblak; Llorente, Le Normand, Giménez, Hancko, Gonzalez; Barrios, Koke, Baena; Griezmann, Alvarez.

Arsenal vs Atlético Madrid Prediction 

  • Pick: Arsenal
  • Odds: -159 (20Bet)
  • Correct score prediction: Arsenal 1-0 Atlético Madrid

It’s been a reliable start to the new season for Arteta’s side. Arsenal have built their success on a solid defensive record, but have often struggled to find creativity in the final third. 

Against a defensive-minded Atlético this week, the Gunners may require a lot of patience to get over the line, but their ability to keep hold of the ball and bide their time to create chances could be vitally important. 

For that reason, we like the chances of a home win when making an Arsenal vs. Atlético Madrid prediction. 

Arsenal vs Atlético Madrid Prediction, Betting Tip

  • Pick: Under 2.5 Goals
  • Odds: -104 (20Bet)

One of the best value angles could come in the form of under 2.5 goals. Arsenal’s matches in 2025-26 have seen an average of 2.25 goals per outing. 

Meanwhile, their success has been built on a solid defensive record, with just 0.25 goals conceded per home game. 

They should be capable of keeping a clean sheet against Atleti on Tuesday, as the Spanish visitors are expected to adopt a cautious approach, looking more than happy to take a point from London. 

Arsenal vs Atlético Madrid Where to Watch (USA, Canada) 

  • CBS (USA)
  • DAZN (Canada)

 Disclaimer: The content provided on this page, including all soccer predictions, odds, and related information, is for entertainment and informational purposes only. While we strive to ensure accuracy and timeliness, we do not guarantee the correctness or reliability of any predictions, data, or information presented here.