Best Strategies for Betting on the MLS

Major League Soccer (MLS) has become one of the most popular football leagues in the world. It can be partially attributed to the calibre of players they feature, including Lionel Messi, Luis Suarez, and Olivier Giroud.

With its growing support, online sportsbooks feature various betting markets on the championship. Ready to find out more? Here’s everything you need to know before you bet on MLS.

Understanding MLS Betting Basics

Established in 1996, MLS is the top-notch league in the United States and Canada. The LA Galaxy lead the league with the most titles (6). 

So, how do we take advantage of information like this? Let’s go through the basics of how to bet on this prestigious tournament.

Differences Between MLS and Other Soccer Leagues

I follow MLS and top European Leagues, and can safely say there are slight differences, particularly in the gameplay. Unlike Europe, MLS games often feature slower transitions and less aggressive pressing. Interesting right!

Additionally, the League operates on a franchise model without promotion and relegation. The schedule is also different. MLS runs from late Winter to Fall, quite a change from the traditional European calendar. 

Key Factors to Consider in MLS Betting Strategy

Below are the most significant factors you’ll need to take into account before placing a wager:

Team Form and Performance Trends

Always check a team’s recent results and how they’ve been doing. Have Inter Miami scored a lot of goals and displayed dominance? It might be a good idea to back this club in your betslip.

Player Injuries and Suspensions

This is a pivotal aspect. A lot of bettors don’t even check whether there is a player injured. Wouldn’t you agree that if Tai Baribo from Philadelphia Union were suspended, it would affect the overall result? 

In such cases, the coach might turn to rotations, and you might reconsider your bet. I’d say that’s worth knowing.

Coaching Strategies and Tactics

Not every manager follows the same strategy and formations. Some focus on the defense, while others prefer the attack. For you to better understand the different styles, check how the respective teams perform in the MLS.

Travel and Scheduling Impact on Performance

In the United States, some regions are far apart from others. This will, for sure, result in fatigue and impact the visiting team’s performance. It might also lead the coach to make some lineup adjustments. 

Scheduling shouldn’t be forgotten either. Some clubs that participate in other competitions might have a busy schedule and be focused on more important encounters. 

Popular Major League Soccer Betting Markets

Here are the most popular betting markets for MLS matches:

• Moneyline: Bet on home win, draw, or away win.
• Over/Under Goals: Predict the total number of goals
• Both Teams to Score: Wager on whether both sides will score
• Possession-Based Props: Guessing which team will have the advantage in possession

Soccer Statistical Analysis for Major League Soccer

You need statistics in MLS. Let’s go through them separately.

Importance of Data and Analytics in Soccer Betting

​From my experience, information and analytics help make more informed decisions and reduce reliance on intuition alone. By analyzing historical data, player performance, and match conditions, you will find patterns that may not be apparent at first glance. 

Advanced Metrics for MLS Betting

Key variables include Expected Goals (xG) and Expected Assists (xA). Additionally, shot conversion rates can reveal inefficiencies in team performance.

Using Historical Data to Predict Outcomes

Check historical data for consistency when you’re betting. ​Let’s say there’s a game between Atlanta and Cincinnati. If Atlanta have been losing a lot recently against their rivals, then it’s a good idea to avoid placing any bet in their favor. 

Bankroll Management for MLS Bets

I can’t say it enough: always stick to your bankroll. If you decide to spend $100 in a single day, don’t exceed the amount even if you’ve lost. With 20Bet’s no deposit bonuses, you can take advantage of their offers to avoid risking real funds.

In-Play Strategies for Major League Soccer Betting

Here are some tips on how to bet on soccer with proper strategies in live MLS matches:

How to Identify Value in Live Betting?

​To identify value with betting odds, watch MLS matches closely. For instance, if Inter Miami are trailing, the odds may still favour the underdog, presenting a potential value opportunity. 

Best Moments to Place In-Play Bets

I would advise placing a wager after the goal has been scored, as the momentum can shift dramatically. If a favorite concedes early, their odds may increase. Factors like red cards can also be key to making successful bets. 

Common Pitfalls in Live MLS Bets

Despite its convenience, live betting has some drawbacks. First of all, you have to follow the event closely. Even the slightest change can shift the odds. Also, I’ve seen a lot of bettors reacting impulsively to early goals, and eventually, they make reckless choices. Don’t get drawn in emotionally.

Impact of Home and Away Performance in MLS

Without question, home soil plays an important role in MLS games. ​For instance, this season, home teams have won approximately 44% of matches, while away teams have secured victories in only about 30%. The difference is clearly visible.

Among the best teams that demonstrate strong performance at home are the Seattle Sounders and Charlotte. Of course, it’s not a guarantee that these clubs will win all the time, but overall, it significantly impacts the outcome. 

Bonuses and Promotions for MLS Betting at 20Bet

While there are no tailored MLS promotions on the sportsbook’s platform, you can grab a 20Bet bonus on your initial deposit. At the same time, the brand offers Weekly Forecast and Bettors Tournament. Entering the 20Bet promo code is not always necessary. Occasionally, you might find customised bonuses, like when the playoffs start.

Responsible Gambling

Even though we strive to provide the ultimate accuracy of our picks, it’s not a guaranteed 100% win. Given the unpredictability of soccer, even the favourites can lose against underdogs in the MLS. This can cause emotional reactions when you need a clear head.

If you notice that your gambling habits are getting out of hand, contact 20Bet’s customer support. They’ll help you set limits on your account and assist with temporary self-exclusion. Stick to your budget, and always gamble responsibly. \

By Kai Iliev

Updated: 29 Apr 2025, 10:59